Current management and future perspectives of overactive bladder (OAB) pharmacotherapy.
نویسندگان
چکیده
Overactive bladder (OAB) is a condition characterized by urgency with or without urgency incontinence (UI), usually with increased daytime frequency and nocturia, which affects even 8-14% of adult population. The gold standards of OAB treatment are antimuscarinics, although this clinical entity is often poorly controlled with these agents. Thus, a progress in OAB pharmacotherapy is expected and takes place. The purpose of this article is to short review the present management of the overactive bladder with paying special attention on development of new drugs indicated for OAB treatment.
منابع مشابه
Postmenopausal overactive bladder
Bladder storage symptoms have a severe impact on many areas as regards the quality of life including health-related, social, psychological and working functions. Pharmacotherapy of lower urinary tract stores (LUTS) has been developed to optimize neural control of the lower urinary tract in pathologic states. The bladder can be overactive or underactive. Overactive bladder (OAB) is highly preval...
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Overactive bladder (OAB) is a common and chronic condition that impacts patients' daily activities and quality of life. Pharmaco-therapy for OAB is a mainstay of treatment. Antimuscarinics and β3-adrenoceptor agonists are the two major classes of oral pharmacotherapy and have similar efficacy for treating the symptoms of OAB. Owing to the chronic nature of OAB, long-term use of medication is es...
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Overactive bladder syndrome (OAB) is a lifestyle disease and its incidence increases with age. Although it is not a life-threatening disease, it is known to have a significant impact on the quality of life. The first-choice pharmacological treatment of OAB is antimuscarinics. However, their limited clinical effectiveness and unsatisfactory tolerance profile, combined with the advancement of kno...
متن کاملMedical management of overactive bladder.
Overactive bladder (OAB) with or without urinary incontinence is a common condition in both men and women. OAB has a significant impact on quality of life for most patients. In most cases, sophisticated testing is not required for a primary care physician to diagnose OAB and start treating a patient. Management of OAB requires behavioral modification and, if necessary, pharmacotherapy may be...
متن کاملOveractive bladder syndrome: Current pathophysiological concepts and therapeutic approaches
OBJECTIVES The overactive bladder syndrome (OAB) is a highly prevalent and bothersome symptom complex. We review contemporary reports to provide an update of the key aspects of its pathogenesis and the therapeutic approaches. METHODS The PUBMED database was searched for relevant publications in the period from 1 January 1985 to 1 May 2013, using the keywords 'overactive bladder', 'anti-muscar...
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ورودعنوان ژورنال:
- Acta poloniae pharmaceutica
دوره 68 6 شماره
صفحات -
تاریخ انتشار 2011